In addition to galectin-3, other markers such as Hector Battifora mesothelial cell-1 (HBME-1), cytokeratin-19 (CK19), and cluster differentiation antigen 56 (CD56) can facilitate the diagnosis of thyroid carcinoma in both histologic and cytologic preparations (62–64, 71) (Figure 6). The gene discussed is LGALS3; the disease is thyroid gland carcinoma.