Interestingly, after adjusting for age, pre-pregnancy BMI, and SBP, our findings indicated that the SNP rs13266634 in SLC30A8 was found to have a protective effect against GDM risk in subjects aged ≥30 years under the recessive and homozygous dominant genetic models, while SLC30A8 rs2466293 was significantly associated with increased GDM risk in patients aged ≥30 years under the dominant and heterozygous dominant genetic models. This evidence concerns the gene SLC30A8 and gestational diabetes.