Second, we find significant associations between TAMs (Iba1, CD68, TREM2, CD32a) and CD8+ T cells specifically in the tumour margins rather than the tumour core, suggesting TAMs may contribute to immune suppression of CD8+ T cells more strongly at the invasive front of glioblastoma and that this region warrants further exploration for stratification of patients in clinical trials. This evidence concerns the gene CD68 and glioblastoma.