So far, biological functions of miR-149 were related to direct interactions with AKT1 (Zhang et al., 2014) or the Fas ligand (Tian and Yan, 2016), which resulted in tumor suppression in hepatocarcinoma patients or the induction of the apoptotic pathway in an acute myeloid leukemia cell line. This evidence concerns the gene AKT1 and neoplasm.