MKI67 and neoplasm: Tumor volume at resection (P=0.98), time from presentation to resection and tumor growth rate after PVE (P=0.06), (P=0.19) were not statistically significant among PVE group compared to controls. Ki67 proliferation index (P= 0.048) was significantly higher than in controls. The 5-year survival rate in PVE vs control group: 25% vs. 55%; The median DFS in PVE vs control groups: 12 months vs. 24 months.