BIRC5 and neoplasm: Fluorinated alkyl chains have been shown to facilitate gene transfection and intracellular protein delivery owing to their hydrophobic and lipophobic characteristics.[181] Xu et al. synthesized acid‐responsive polycation (ARP) and then modified ARP with fluorinated alkyl chains to produce ARP‐F.[104b] The delivery of pCas9‐survivin plasmid using ARP‐F exhibited strong tumor inhibition in A549 tumor‐bearing BALB/c nude mice.