The miR‐155 can effectively reprogram tumor‐supportive M2‐like TAMs to anti‐tumor M1 phenotype by up‐regulating expressions of miR‐155 in TAMs, M1‐related IL‐12, iNOS, and MHC II markers, and suppressing M2‐related Msr2 and Arg1 markers, which resulted in an obvious regression of B16 tumor.[129] Huang et al. This evidence concerns the gene ARG1 and neoplasm.