IFNG and neoplasm: adhered the cell‐adhesive layer‐ stabilized IFN‐γ BPs to the surface of macrophage (BMDM), which could sustainably promote anti‐tumor M1‐polarization even in an immunosuppressive TME, resulting in robust regression of breast tumor and metastasis.[240] More importantly, the resultant IFN‐γ‐macrophage‐BPs could evade phagocytosis of macrophages for several days and maintain the activity of IFN‐γ for a long time, which suggests the great potential of engineering TAMs‐repolarization agents‐loaded macrophage‐BPs to enhance anti‐tumor therapy.