MMP2 and neoplasm: developed matrix MMP2‐sensitive phosphatidylserine (PtdSer) modified nanoparticles, which were loaded with the anti‐tumor drug dasatinib as a TAMs‐depleting agent.[79] After the nanoparticles were accumulated in the MMP2 overexpressed tumor environment, the PtdSer was inversed from inside to outside to be specifically phagocytosed by TAMs, because externalization of PtdSer on the apoptotic cell membrane is a well‐known “eat me” signal to attract macrophages recognizing and phagocytosing apoptotic cells.