CD4 and neoplasm: It is also worthy noted that MerTK is also expressed on CD4+ and CD8+ T cells, which plays costimulatory role in promoting activation and function of T cells.[232] Therefore, blocking macrophage‐mediated MerTK signaling of efferocytosis would impair functions of tumor‐specific T cells.[232] Thus, development of nanotechnology for targeted inhibition of macrophages‐mediated efferocytosis is indeed necessary.