fabricated a photothermal‐activatable in situ self‐assembled nanomicelle dissolving microneedle (DMN) patch based on hyaluronic acid (HA) to deliver autophagy inhibitor (chloroquine, CQ) and ICD‐inducer (IR780) to deep tumor via the interaction of HA with CD44 receptor.[118] The resultant nanomicelle could promote M2‐like TAMs‐repolarization through CQ‐mediated autophagy inhibition to activate NF‐κB signaling pathway and thus suppress the primary and distant melanoma tumor progression in synergy with localized photoimmunotherapy. This evidence concerns the gene NFKB1 and melanoma.