demonstrated that cypermethrin (CYM) can facilitate M2‐like macrophages polarization by inhibiting expression of miR‐155, which subsequently triggered Lewis lung cancer cells metastasis.[130] It has been demonstrated that enforcing expression of miR‐125b can make macrophage susceptible to IFN‐γ stimulation by inhibiting expression of IRF4, which is a positive modulator of M2‐like macrophages.[53, 131, 132] Additionally, depletion of DICER, a miRNA‐processing enzyme, can promote repolarization of M2‐like TAMs into M1 phenotype in MC38 and LLC tumor models.[133]. Here, IFNG is linked to neoplasm.