reported that engineered M1 macrophages carrying oxaliplatin prodrug and photosensitizer were able to be activated by near‐infrared light to generate cytotoxic ROS (Figure 8B).[142] Photodynamic treatment was able to eliminate tumor cells, which then produced tumor‐associated antigens, triggering an anti‐tumor immune response and facilitating anti‐PD‐L1 immune checkpoint blockade. Here, CD274 is linked to neoplasm.