C9orf72 and amyotrophic lateral sclerosis: Sequestration of hnRNP H might affect the expression of mRNAs containing G4-RNA motifs, and hnRNP H associates with G4-forming C9orf72 repeats and co-localizes with G4 foci in cells derived from patients with amyotrophic lateral sclerosis (ALS) but not in non–ALS-derived cells.