MA and Liu's team found that high expression of the tumor cell-intrinsic E3 ligase TRIM7 was associated with poor prognosis in nasopharyngeal carcinoma by inhibiting mitochondrial DNA release and affecting STING-STING/1 type interferon signaling, thereby impairing CD8 T cell-mediated antitumor immune responses and causing resistance to radiation therapy [38]. The gene discussed is STING1; the disease is neoplasm.