In previous studies, the prognosis in SC-EPN was better than PFA-EPN and EPN-ZFTA [22], and the prognosis of GBM was the worst among SC-EPN, PFA-EPN, and EPN-ZFTA [24], while the expression of Iba-1 and CD204 was the highest in GBM and the lowest in SC-EPN in the present study. The gene discussed is AIF1; the disease is glioblastoma.