HDAC1 and leukemia: The same experiment performed using the leukemia cell line MV4-11 validated HDAC1 (Kdapp = 16 μM), HDAC2 (Kdapp = 14 μM), and HDAC6 (Kdapp = 21 μM) and identified HDAC3 (Kdapp = 13 μM) and HDAC10 (Kdapp = 5 μM) as additional targets of (R/S)-LM (Fig. 1d).