We knocked down MGST1 in SK-Mel-28 cells with pLKO.1 shRNA lentiviral particles and overexpressed MGST1 in 1205Lu cells with pCDH MGST1 lentiviral particles and showed that in amelanotic melanoma cells, dopachrome formation correlated with the amounts of MGST1 (Fig. 1, J–L). Here, MGST1 is linked to melanoma.