ITGAX and infection: There was no significant difference in the frequency of neutrophils in the blood of uninfected or 14 dpi Atg5fl/fl and Atg5fl/fl-CD11c-Cre mice (S1A Fig), suggesting that the accumulation of neutrophils in the lungs of M. tuberculosis-infected Atg5fl/fl-CD11c-Cre mice was due to specific recruitment of neutrophils to the site of infection or an inability to clear neutrophils from the lung.