TNF and tuberculosis: Similarly, the CD19+ T cell phenotypes were not different between groups when stimulated with SufR in the short term or 7-day assays (S3 Fig in S1 File), while multifunctional CD19+IFNg-IL2+IL10-TNFa- B cells were significantly increased in the QFN pos group (p = 0.02) when compared to active TB following 12-hr SufR stimulation (S6 Table in S1 File).