TLR4 and infection: At one day post-infection, the number of E. coli in leptomeninges flatmounts did not differ significantly between C57 WT control and Ccr2-/- mice, whereas the number of E. coli in leptomeninges flatmounts was increased ~twofold in Tlr4-/- mice, albeit with substantial scatter in the data (Figure 1—figure supplement 3C, center plot).