Neoadjuvant chemotherapy is now a common practice for breast cancer patients, and the association of TILs with pCR after chemotherapy in HER2-positive breast cancer and TNBC is widely known.33,48,49 Stromal TILs are usually measured in this context, and few investigations have studied intratumoral TILs. The gene discussed is ERBB2; the disease is breast cancer.