AURKB and neoplasm: Moreover, activation experiment of SC-79 in vivo revealed that SC-79 promoted the tumor growth and lung metastasis of HCCC9810- AURKB-KD mice, whereas inhibition experiment of MK-2206 in vivo showed that MK-2206 inhibited the tumor growth and lung metastasis of RBE AURKB-OE mice (Additional file 4: Fig. S4A–C).