Approximately 35% of patients with an MRT have been diagnosed with germline alterations of a single allele of the hSNF5 gene, and those who carry a germline mutation in either hSNF5 or BRG‐1 tend to be at greater risk to develop the MRT, known as rhabdoid tumor predisposition syndrome (RTPS).80, 81, 82. The gene discussed is SMARCB1; the disease is familial rhabdoid tumor.