In addition, serum hyaluronic acid (HA), which is an essential component of the extracellular matrix and is correlated with liver fibrosis, α‐2‐macroglobulin (A2M), and procollagen III amino terminal pro‐peptide (PIIINP), and serum biomarkers of liver fibrosis and fibrogenesis were used to evaluate the degree of liver fibrosis. Here, A2M is linked to Hepatic fibrosis.