The purpose of this study was to correlate conventional MRI features with homozygous deletion of CDKN2A and/or CDKN2B, type of IDH mutation (IDH1-R132H or non-canonical) and overall survival in a cohort of histological grade 2–3 IDH-mutant and 1p/19q-non-codeleted astrocytomas. The gene discussed is IDH2; the disease is astrocytoma (excluding glioblastoma).