Furthermore, only a minority of such research has specifically examined imaging features associated with CDKN2A/B status in IDH-mutant astrocytomas that would otherwise be considered grades 2–3 [23], which is the group of gliomas for which CDKN2A/B is most relevant according to the 2021 classification [2]. The gene discussed is CDKN2A; the disease is astrocytoma (excluding glioblastoma).