Interestingly, wild-type PTPN22 (rs2476601 c.1858CC) combined with FCRL3 rs7528684 NG_023241.1:g.4832CC was previously associated with higher HbA1c at diagnosis but lower HbA1c at the sixth and later months in patients with type 1 diabetes mellitus [43]. The gene discussed is PTPN22; the disease is type 1 diabetes mellitus.