Microglial cells treated with CM from shCTRL-transduced GBM expressed high levels of angiopoietin 2, IGFBP6, CD142, LIF, NGAL (MMP9), CSF-1, MMP2, CCL5, Col18a1, TNFRSF11B, and CXCL2. The gene discussed is LCN2; the disease is glioblastoma.