To investigate CCR7 expression in malignant gliomas in silico, we used multiple data sources from The Cancer Genome Atlas (TCGA) database (TCGA LGGGBM microarray and GBM RNAseq), a tissue microarray (TMA) of 153 primary CNS tumors and 11 normal brain samples, and the RNA database from a primary glioma patient cohort (25 patients, 14 GBMs and 11 LGGs). This evidence concerns the gene CCR7 and central nervous system cancer.