LncRNA PCAT1 interacts with dyskerin pseudouridine synthase-1 (DKC1) to activate the vascular endothelial growth factor (VEGF)/protein kinase B (AKT)/Bcl-2/caspase-9 pathway and promote the transcription and translation of Bcl-2, contributing to enhancing abilities in proliferation and invasion of non-small cell lung cancer cells and inhibiting apoptosis of tumor cells (30). This evidence concerns the gene AKT1 and neoplasm.