Of note, the low affinity receptor for immunoglobulin G (FcγRIIIA, CD16) also contributes to tumor clearance, as revealed by the augment of antibody-dependent cell-mediated cytotoxicity (ADCC) by NK cells upon the use of therapeutic IgG monoclonal antibodies (Mentlik James et al., 2013; Battella et al., 2016). The gene discussed is FCGR3A; the disease is neoplasm.