The expression of CD3D, CD86, CTLA4, GATA3, HAVCR2, IFNG, ITGAM, LAG3, NRP1, PDCD1, STAT5A, and TGFB1 was significantly higher in high-risk population, suggesting that the risk model based on PANoptosis-related genes was associated with HCC immune cell infiltration (Figure 4(e)). This evidence concerns the gene CTLA4 and hepatocellular carcinoma.