It has been also demonstrated that BST-1/CD157 is involved in the progression and differentiation of leukemia (23–25), metastasis of ovarian carcinoma cells (26–28), malignant mesothelioma (29, 30) and glioma (31), and thus could be used as diagnostic or prognostic markers. The gene discussed is BST1; the disease is malignant mesothelioma.