Of the 24 statistically significant factors found in the univariate analysis, the 15 factors with a p-value of <0.05 (CRP >2.12 mg/dL, sex, age, Wagner grade, hypertension, heart failure, hypercholesterolaemia, HTG, haematocrit <33%, WBC count >10.2×103/μL, platelet count >318×103/μL, atherosclerotic peripheral arteries, albumin <3.5 g/dL, GFR<30 mL/ min/1.73 m2 and pathogenesis) were applied in the multivariate analysis. The gene discussed is CRP; the disease is hypertensive disorder.