Of the risk factors found in the univariate analysis, 15 (CRP >2.12 mg/dL, sex, age, Wagner grade, hypertension, heart failure, hypercholesterolaemia, HTG, haematocrit <33.0%, WBC count >10.2×103/μL, platelet count >318×103/μL, atherosclerotic peripheral arteries, albumin <3.5 g/dL, GFR <30 mL/min/1.73 m2 and pathogenesis) were applied in multivariate analysis. Here, CRP is linked to heart failure.