CRP and infection: There have been several studies to find blood markers that can inform infection severity when making the decision for amputation.26–29 In our univariate analysis, levels of CRP >2.12 mg/dL, platelet counts >318×103/μL, WBC count >10.2×103/μL and blood albumin levels <3.5 g/ dL were important markers of infection severity predicting amputation.