APOF and neoplasm: For PRAD, the mRNA expression of APOF was negatively associated with TMB (R = − 0.09), MSI (R = − 0.10), NEO ((R = − 0.10), tumor ploidy (R = − 0.18), HRD (R = − 0.23) and LOH (R = − 0.12) (Fig. 3A–H).