Besides, this lncRNA is involved in the cisplatin resistance for gastric tumor with downregulated expression via the SLC7A11-AS1/xCT axis [35]; nevertheless, downregulation of SLC7A11-AS1 can significantly decrease the NRF2/SLC7A11 expression and inhibit the progression of colorectal cancer [36]. The gene discussed is PTGDR; the disease is colorectal cancer.