Patients who reached the composite PEP had lower systolic and diastolic blood pressure, had a higher NT-proBNP (303 [180–540] vs. 71 [26–166] pmol/L, p < 0.001), and comorbidities such as atrial fibrillation and renal failure were more prevalent in this group (resp. This evidence concerns the gene NPPB and acute kidney injury.