In agreement with our findings using ROBO1 KO macrophages, N-SLIT2 had no effect on phosphorylation of p70S6K in human DLD-1 adenocarcinoma cells which completely lack the N-SLIT2-binding Roundabout receptors (Zhou et al, 2011) (Fig S1A–C). The gene discussed is ROBO1; the disease is adenocarcinoma.