Genetic and pharmacologic interventions that mitigate neointimal hyperplasia almost always mitigate atherosclerosis—as we (3, 4, 12, 16, 17, 48, 49, 50) and others (51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63) have shown, including with USP20 itself (3, 4). The gene discussed is USP20; the disease is atherosclerosis.