As shown in Table 2, C statistics for all-cause dementia varied between 0.59 (95% CI, 0.58-0.60) for ANU-ADRI and 0.73 (95% CI, 0.72-0.73) for CAIDE–APOE-supplemented, but it was higher (C = 0.79; 95% CI, 0.79-0.80) for the model including only age. This evidence concerns the gene APOE and dementia.