A study on the diagnostic and prognostic value of cytokines in sepsis and septic shock revealed that IL-6 can differentiate sepsis from nonsepsis; moreover, in patients with septic shock, IL-6 levels were significantly higher than those in patients with sepsis, and IL-6 > 348.9 pg/ml was an independent risk factor for a poor prognosis in patients with septic shock [21]. The gene discussed is IL6; the disease is Shock.