While the expression of guanylate-binding protein 1 (GBP1), interferon-gamma inducible protein 16 (IFI16), interferon-induced protein with tetratricopeptide repeats 2 (IFIT2), interferon-induced transmembrane protein 1 (IFITM1), and MX dynamin-like GTPase 1 (MX1) was increased in COVID-19-derived PBMCs (Fig. 4C), the expression of APOBEC3A, GBP1, IFIT1, IFITM1, ISG15, MX1, and OAS1 was increased in COVID-19-derived monocytes (Fig. 5B). The gene discussed is IFI16; the disease is COVID-19.