rTvActin polymerizes into F-actin in vitro at a critical concentration of 2 μM, which is slightly lower than that of 4 μM measured for Act1 of the malaria parasite Plasmodium falciparum (PfAct1) but an order of magnitude higher than that of mammalian skeletal actin (44). This evidence concerns the gene TRAF3IP2 and malaria.