Serum levels of AST, ALT, AST/ALT ration as well as liver fibrosis score, APRI and LAP decreased greater in DASH group than control group, nevertheless, after adjusting for baseline values and weight change, only the reductions in serum AST, APRI and LAP did reach to statistically significant level (P = 0.008, P = 0.019 and P = 0.003, respectively). This evidence concerns the gene GPT and Hepatic fibrosis.