Next, we measured depression‐related behaviors without stress and found that AAV‐CaMKII‐Cre‐treated mice showed nearly the same sniffing time for water or female urine as AAV‐CaMKII‐GFP‐treated mice (Figure S7C, treatment: F(1,16) = 0.1887, p = 0.6698; sniffing object: F(1,16) = 86.7700, p < 0.0010; treatment × sniffing object, F(1,16) = 0.0328, p = 0.8586), with no changes observed in sucrose preference for these two groups (Figure S7D, t(16) = 1.0340, p = 0.3163). Here, CAMK2G is linked to depressive disorder.