PPM1F and major depressive disorder: Furthermore, the reduced protein levels of PPM1F in the mPFC was only found in male, but not female mice (male: t(18) = 6.4450, p < 0.0010; female: t(15) = 0.4379, p = 0.6677; Figure 1E, Figure S1C), which was also positively correlated with depression‐related behaviors (Figure 1E).