Further, compared with married patients, unmarried patients were less likely to have traditional cardiovascular comorbidities such as diabetes mellitus, smoking, peripheral vascular disease, chronic kidney disease, and ischemic heart disease and were less likely to be chronically prescribed with angiotensin receptor binders, mineralocorticoid receptor antagonist, statins and antithrombotic medications. The gene discussed is NR3C2; the disease is chronic kidney disease.