To elucidate the role of HNRNPA2B1 in NSCLC, we constituted HNRNPA2B1-kockdown cell models in 95D and H1299 cell lines with shRNA, and HNRNPA2B1-overexpression cell models in A549 and PC-9 cell lines with plasmids. The gene discussed is HNRNPA2B1; the disease is non-small cell lung carcinoma.