SKP2 and cancer: Particularly, SKP2 expression had a remarkable capacity to differentiate eight cancers from their control tissues; the eight neoplasms were BLCA, CESC, COAD, ESCA (esophageal carcinoma), GBM (glioblastoma multiforme), LUSC, PCPG (pheochromocytoma and paraganglioma), and READ (AUC > 0.90) (Fig. 7A).