ESR1 and breast carcinoma: In both age-adjusted (Model 1) and multivariable models (Model 2), heavier alcohol consumption was associated with an increased odds of any invasive breast cancer [multivariable OR (95% CI): 1.30 (1.00–1.68)], ER- breast cancer [OR (95% CI): 1.48 (1.01–2.14)] and PR- breast cancer [OR (95% CI): 1.50 (1.07–2.10)]; the comparable OR for ER + breast cancer was 1.33 (0.98–1.82)).