CD274 and cancer: A study by Cocks M et al. in which standard TPS or CPS was not used, instead a cutoff of 1% positive cells was used, showed that PD-L1 expression was found in 43% of tumor cells, with higher proportions in intratumoral (67%) and peritumoral (81%) immune cells [30], and higher PD-L1 expression and high CD8 + TILs were associated with disease recurrence, overall mortality, and cancer mortality [30].