We also found that CLEC1B had a highly positive correlation with the degree of immune infiltration of most infiltrating lymphocytes, including monocytes, Th1 cell, Th17 cell, Act B cell, Tem CD8, Act CD8, macrophage, neutrophil cell, eosinophil cell, NK cell, Treg cell, Tgd cell, and others; indicating that CLEC1B most likely participates in the development and survival status of HCC by changing the TME. The gene discussed is CLEC1B; the disease is hepatocellular carcinoma.