Local ischemia and hypoxia in the retina cause an increase in the concentration of cytokines, including vascular endothelial growth factor (VEGF) and inflammatory factors, resulting in fluid accumulation in the inner and lower layers of the retina by disrupting the blood-retinal barrier to promote neovascularization and macular edema (ME) [1, 2]. Here, VEGFA is linked to macular retinal edema.