NELL1 and nervous system disorder: Ultimately, we screened 15 genes based on the intersection obtained by XPEHH, iHS and Fst, namely CSMD1, EXOC4, GALNT18, GALNTL6, HLA-DRA, JAZF1, KCNQ1, LINC00486, LRP1B, NELL1, OPCML, RBFOX1, SMYD3, STK32B and TENM4. These targeted loci were used as the top selected adaptive genes, whose annotation information was mainly associated with the immune system and neurological disorders (Fig. 5A and Table S10).