For instance, Peng et al reported that HOXD‐AS2 can activate cell cycle to promote glioma progression14; HOXD‐AS2 can also promote glioblastoma cell proliferation, migration, and invasion by regulating the miR‐3681‐5p/MALT1 signaling pathway15, 16; You et al found that TGF‐β1‐induced HOXD‐AS2 can competitively bind to KSRP to regulate MGMT expression and TMZ resistance.17 The gene discussed is HOXD-AS2; the disease is central nervous system cancer.