Oculofaciocardiodental (OFCD) syndrome (MIM#300166), also called microphthalmia syndromic 2, is caused by variants in the BCL6 corepressor (BCOR) gene located at Xp11.4 and has male-lethal, X-linked, dominant inheritance1. The gene discussed is BCOR; the disease is microphthalmia, Lenz type.