SLC1A3 and Alzheimer disease: Slc1a3, encoding for the excitatory amino acid transporter 1 (EAAT1), was among the genes significantly increased by repeated alcohol intoxication in astrocytes of 3xTg-AD mice exposed to alcohol versus WT controls but not in 3xTg-AD mice or WT mice exposed to alcohol versus WT controls (Extended Data Fig. 4-1).